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Nexum Capsules 40Mg (1 Strip = 7 Capsules)
Rs.322.00
SKU
Nexum Capsules Specification
Requires Prescription (YES/NO)
Yes
Generics
Esomeprazole
Used For
Acidity & Ulcers
How it works
Esomeprazole works by binding irreversibly to the H+/K+ ATPase in the proton pump. Because the proton pump is the final pathway for secretion of hydrochloric acid by the parietal cells in the stomach, its inhibition dramatically decreases the secretion of hydrochloric acid into the stomach and alters gastric pH .
Nexum Capsules Usage And Safety
Dosage
Esomeprazole
Side Effects
Headache , GI upset , Skin reactions , Dry mouth. Rarely angioedema . Rarely angiooedema , anaphylaxis , fundic gland polyps.
Drug Interactions
Phenytoin , warfarin , clopidogrel , ketoconazole , itraconazole , voriconazole , diazepam , citalopram , imipramine , clomipramine , CYP3A4 inhibitors or inducers , tacrolimus , digoxin , erlitinib , methotraxate
Indication
Treatment of Heartburn , GERD , Gastritis & Ulcer
When not to Use
It is contraindicated in patients with known hypersensitivity to proton pump inhibitors (PPIs). Hypersensitivity reactions e.g. angioedema and anaphylaxis, bronchospasm, acute interstitial nephritis and urticaria have been reported with esomeprazole use.
Nexum Capsules Precautions
Precaution
Daily long-term use (e.g. longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin.
Nexum Capsules Warnings
Warning 1
Hypomagnesemia has been reported rarely with prolonged treatment with PPIs.
Warning 2
Long-term and multiple daily dose PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine.
Warning 3
Avoid concomitant use of Esomeprazole with clopidogrel.
Nexum Capsules Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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